Defensins Labs

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Last updated: 3rd February 2010

InvestigatorInstitutionResearch Interest
Lu WuyuanInstitute of Human virology - University of Maryland Biotechnology Institute - Baltimore MarylandDevelopment of peptide/protein therapeutics for the treatment of cancer and infectious diseases by using immunological molecules such as defensins.
Lubkowski JacekNational Cancer Institute at FrederickCorrelating structures of defensins with their antimicrobial and chemotactic properties.
McDermott Alison M.College of Optometry - University of HoustonExpression and roles of cationic antimicrobial peptides at the ocular surface.
Nagaraj RamakrishnanCentre for Cellular and Molecular Biology - Hyderabad India
Natori ShunjiGraduate School of Pharmaceutical Sciences - The University of Tokyo - Japan; Natori Laboratory - The Institute of Physical and Chemical Research (RIKEN) - JapanFunctional characterization of antimicrobial peptides in flies, such as the sapecins in the flesh fly Sarcophaga peregrina.
Noga Edward J.Department of Clinical Sciences - North Carolina State UniversityIdentification of novel innate antimicrobial defenses (polypeptide antibiotics) in fish and shellfish.
Oppenheim Joost J. National Cancer Institute - Center for Cancer ResearchRole of chemokines in inflammation, immunity, and chemokine mimics such as defensins and autoantigens.
Ouellette Andre J. Department of Pathology and Laboratory Medicine - University of California IrvineRole of phagocyte and Paneth cell alpha-defensins in innate immunity in small intestine epithelium. Structure-activity relationships and biochemical regulation of mouse and primate alpha-defensins and their precursors.
Periathamby Antony RajSchool of Dentistry - Marquette University
Roch PhilippeLaboratoire Defense et Resistance chez les Invertebres Marins (DRIM) - Institut pour l'Exploitation de la Mer (IFREMER) - Universite de Montpellier II - FranceStudy of the immune systems of mussels and oysters, with particular interest in the pharmacophores and modes of action of their defensins.